After signing in on a website the console log outputs error "Unchecked runtime.lastError: The message port closed before a response was received".
Disabling the 1Password extension resolves the issue.
This bug appeared since Chromium update 72.0.3626.81 as of January 29th.
Please check in to this because console log errors are a PITA for a developer;-)
1Password Version: 6.8.8
Extension Version: 22.214.171.124
OS Version: OS X 10.14.2
Sync Type: ICloud