I've tried this using Chrome 18 and 19.0.1084.46. I can bring up the 1password extension using ctrl+\ in my main user. When I change Chrome user ( https://support.google.com/chrome/bin/answer.py?hl=en&answer=2364824
) I can no longer use the shortcut and instead have to goto the 1password icon. If I switch back to the default user the shortcut works.