I’ve tested 1Password X Beta and 1Password on macOS with Google Chrome, no issues. I installed the same 1Password X Beta plugin, from the Google Chrome store, in Microsoft Edge, but unlocking 1Password on macOS does not unlock 1Password X in Edge (but does in Chrome). I know Edge is beta and most likely not officially supported by 1Password. I just wanted to point this out to the team.
1Password Version: 7.3.2 BETA-0
Extension Version: 1.16.5
OS Version: macOS 10.14.5
Sync Type: 1Password for Families