When logging into the AWS Management Console at https://console.aws.amazon.com, after entering details on the first page (account alias, username, password) I am presented with the MFA screen; 1Password X does not fill this and doesn't show a little icon in the field, so I have to either navigate to the OTP in 1Password and copy/paste, or use the old 1Password browser extension.
To test this you'd need to create a (free) AWS account and set up MFA, instructions here: https://docs.aws.amazon.com/IAM/latest/UserGuide/id_credentials_mfa_enable_virtual.html
I'm using 1Password X in Chrome Version 76.0.3809.87
1Password Version: 1.15.6
Extension Version: Not Provided
OS Version: Windows 10 1903
Sync Type: Not Provided