Same thing happens in Firefox and Chrome.
The problem is as stated in the title. I'll start getting "Can't connect to the server" errors whenever I try to save a password, which is fixed temporarily if I uninstall/reinstall the extension. Can't say how long goes in between working and breaking because I'm not often saving new passwords. It's mostly just an annoyance for that reason, but it is annoying.
1Password Version: Not Provided
Extension Version: Not Provided
OS Version: Not Provided
Sync Type: Not Provided